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Keep an eye on Carefully (one)lumefantrine will minimize the level or result of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. For patients acquiring exemestane which has a potent CYP3A4 inducer the encouraged dose of exemestane is fifty mg day-to-day following a food.Adjuvant remedy of postmenopaus